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1.
J Hosp Infect ; 113: 104-114, 2021 Jul.
Article in English | MEDLINE | ID: covidwho-1531580

ABSTRACT

Healthcare-associated infections (HAIs) are the most common adverse outcomes due to delivery of medical care. HAIs increase morbidity and mortality, prolong hospital stay, and are associated with additional healthcare costs. Contaminated surfaces, particularly those that are touched frequently, act as reservoirs for pathogens and contribute towards pathogen transmission. Therefore, healthcare hygiene requires a comprehensive approach whereby different strategies may be implemented together, next to targeted, risk-based approaches, in order to reduce the risk of HAIs for patients. This approach includes hand hygiene in conjunction with environmental cleaning and disinfection of surfaces and clinical equipment. This review focuses on routine environmental cleaning and disinfection including areas with a moderate risk of contamination, such as general wards. As scientific evidence has not yet resulted in universally accepted guidelines nor led to universally accepted practical recommendations pertaining to surface cleaning and disinfection, this review provides expert guidance for healthcare workers in their daily practice. It also covers outbreak situations and suggests practical guidance for clinically relevant pathogens. Key elements of environmental cleaning and disinfection, including a fundamental clinical risk assessment, choice of appropriate disinfectants and cleaning equipment, definitions for standardized cleaning processes and the relevance of structured training, are reviewed in detail with a focus on practical topics and implementation.


Subject(s)
Cross Infection , Disinfectants , Cross Infection/prevention & control , Delivery of Health Care , Disinfection , Equipment Contamination/prevention & control , Humans , Hygiene
2.
Anaerobe ; 71: 102420, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1321979

ABSTRACT

A 42-year-old man was referred to the Department of Orthopedic Surgery with pain over his right greater trochanter and signs of systemic infection. CT showed an enhanced mass in his gluteus maximus as well as gas in the biceps femoris over the underlying hip joint. Tissue biopsy yielded Fusobacterium nucleatum and Actinomyces turicensis. The patient was successfully treated for 6 weeks with amoxicillin/clavulanic acid 875mg/125mg and metronidazole 500mg.


Subject(s)
Actinomycetaceae/isolation & purification , Actinomycetales Infections/microbiology , Bacteremia/microbiology , COVID-19/immunology , Fusobacterium Infections/microbiology , Fusobacterium nucleatum/isolation & purification , Hip/microbiology , Abscess/drug therapy , Abscess/microbiology , Actinomycetaceae/drug effects , Actinomycetaceae/genetics , Actinomycetales Infections/drug therapy , Adult , Anti-Bacterial Agents/therapeutic use , COVID-19/virology , Fusobacterium Infections/drug therapy , Fusobacterium nucleatum/drug effects , Fusobacterium nucleatum/genetics , Humans , Immunocompromised Host , Male , SARS-CoV-2/genetics , SARS-CoV-2/isolation & purification
3.
J Hosp Infect ; 111: 189-199, 2021 May.
Article in English | MEDLINE | ID: covidwho-1083194

ABSTRACT

BACKGROUND: The COVID-19 pandemic not only had an impact on public life and healthcare facilities in general, but also affected established surgical workflows for elective procedures. The strategy to protect patients and healthcare workers from infection by SARS-CoV-2 in surgical departments has needed step-by-step development. Based on the evaluation of international recommendations and guidelines, as well as personal experiences in a clinical 'hot spot' and in a 450-bed surgical clinic, an adapted surgical site infection (SSI) prevention checklist was needed to develop concise instructions, which described roles and responsibilities of healthcare professionals that could be used for wider guidance in pandemic conditions. METHOD: Publications of COVID-19-related recommendations and guidelines, produced by health authorities and organizations, such as WHO, US-CDC, ECDC, the American College of Surgery and the Robert Koch Institute, were retrieved, assessed and referenced up to 31st January 2020. Additionally, clinical personal experiences in Germany were evaluated and considered. RESULTS: Part 1 of this guidance summarizes the experience of a tertiary care, surgical centre which utilized redundant hospital buildings for immediate spatial separation in a 'hot spot' COVID-19 area. Part 2 outlines the successful screening and isolation strategy in a surgical clinic in a region of Germany with outbreaks in surrounding medical centres. Part 3 provides the synopsis of personal experiences and international recommendations suggested for implementation during the COVID-19 pandemic. CONCLUSION: Understanding of COVID-19, and SARS-CoV-2-related epidemiology, is constantly and rapidly changing, requiring continuous adaptation and re-evaluation of recommendations. Established national and local guidelines for continuation of surgical services and prevention of SSI require ongoing scrutiny and focused implementation. This manuscript presents a core facility checklist to support medical institutions to continue their clinical and surgical work during the COVID-19 pandemic.


Subject(s)
COVID-19/prevention & control , Disease Outbreaks/prevention & control , Elective Surgical Procedures/standards , Infection Control/standards , Pandemics/prevention & control , Practice Guidelines as Topic , Surgical Wound Infection/prevention & control , Germany , Humans , SARS-CoV-2
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